Tailored treatments for severe asthma based on specific disease characteristics
University of Kansas' Precision Biologic Interventions for Severe Exacerbation Prone Asthma (PrecISE) Clinical Center
This study is looking at how different kinds of severe asthma respond to specific treatments, so we can find the best options for each person and improve their care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10455084 on NIH RePORTER |
What this research studies
This research investigates how different types of severe asthma respond to targeted biologic therapies. By focusing on specific asthma phenotypes, such as eosinophilic and T2-driven conditions, the study aims to determine which treatments are most effective for each type. Patients will be monitored for their response to these tailored therapies, allowing for a more personalized approach to asthma management. The goal is to establish a new standard of care that improves outcomes for individuals with severe asthma.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with severe asthma, particularly those with eosinophilic or T2-driven phenotypes.
Not a fit: Patients with mild asthma or those who do not have identifiable asthma phenotypes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with severe asthma.
How similar studies have performed: Previous research has shown promise in using targeted biologic therapies for asthma, suggesting that this approach could be effective.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Castro, Mario — University of Kansas Medical Center
- Study coordinator: Castro, Mario
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.