Tailored HIV prevention and care for young couples using alcohol and drugs in Cape Town

Resubmission: Multilevel Strategies & Tailored HIV Prevention & Care for Young Couples who use Alcohol & Other Drugs Across Cape Town

NIH-funded research Research Triangle Institute · NIH-10849677

This study is looking for young couples in Cape Town, aged 18 to 30, who are at risk for HIV because of alcohol and drug use, to try out a supportive program that offers education and access to HIV prevention methods, while also helping clinics be more welcoming to young people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-10849677 on NIH RePORTER

What this research studies

This research focuses on young couples in Cape Town who are at high risk for HIV due to alcohol and drug use. It aims to implement a comprehensive intervention called Couples' Health CoOp Plus (CHC+), which provides education and access to HIV prevention methods like PrEP and ART. The study will involve training clinics to reduce stigma towards young people using substances and will utilize a randomized trial design to evaluate the effectiveness of these interventions. Couples aged 18 to 30 will be recruited from economically disadvantaged communities to participate in this program.

Who could benefit from this research

Good fit: Ideal candidates for this research are young couples aged 18 to 30 living in Cape Town who engage in alcohol and drug use.

Not a fit: Patients who do not use alcohol or drugs or are outside the age range of 18 to 30 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce HIV transmission rates among young couples who use alcohol and drugs.

How similar studies have performed: Previous studies have shown success with similar interventions targeting couples and substance use, indicating a promising approach.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.