Tailored digital program to help people with HIV quit smoking
Hybrid Trial of a Tailored Smoking Cessation Digital Therapeutic for Persons Living with HIV
['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11262181
A smartphone-based program adapted for people living with HIV to help them quit smoking using therapy techniques and guideline-based support.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-11262181 on ClinicalTrials.gov |
What this research studies
You would use a digital therapeutic app called LTQ-H that was designed specifically for people with HIV and focuses on skills from Acceptance and Commitment Therapy plus clinical guideline recommendations. The project runs a hybrid trial that combines testing the app's ability to help people stop smoking with studying how to best deliver the app in real-world HIV care settings. Some parts of the work are remote and some involve clinic partners, and researchers will gather outcomes like quitting and barriers to using the app. The team previously ran a small remote pilot and is expanding to a larger trial and implementation study.
Who could benefit from this research
Good fit: Adults living with HIV who currently smoke cigarettes, are willing to try a smartphone-based program, and can provide follow-up information are ideal candidates.
Not a fit: People who do not smoke, those without HIV, or individuals without access to or comfort using a smartphone or mobile apps may not benefit from this intervention.
Why it matters
Potential benefit: If successful, the program could make effective quitting support widely available to people with HIV and reduce smoking-related illness and premature death in this group.
How similar studies have performed: Digital quitting programs and Acceptance and Commitment Therapy have shown benefit for smoking cessation in the general population and a prior small remote pilot of this tailored app showed promising results.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VILARDAGA, ROGER — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: VILARDAGA, ROGER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus