Tailored community harm-reduction to prevent drug overdoses
Reversing Overdose Epidemics through Simulation, Collaboration, and Unified Efforts (RESCUE)
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-11193985
This project will create local harm-reduction plans—like wider naloxone access, overdose prevention services, drug checking, and detection tools—for communities, with focus on Black and American Indian/Alaska Native populations to help reduce overdose deaths.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11193985 on ClinicalTrials.gov |
What this research studies
As someone worried about overdoses in my community, this project will partner with local health departments and community groups to design harm-reduction programs that fit our area's needs. The team will combine strategies such as expanded naloxone distribution, overdose prevention centers, drug checking services, and overdose-detection technologies and analyze their costs and effects. They will develop and tailor these approaches across six different jurisdictions, building on prior work in Rhode Island, Massachusetts, and New York City, and will include input from affected community members. The emphasis is on practical, locally driven plans that can be put into action where people live and use drugs.
Who could benefit from this research
Good fit: Ideal participants are people and community organizations in the six partnered jurisdictions—especially individuals at risk of opioid overdose and members of Black and American Indian/Alaska Native communities—who can help guide or receive harm-reduction services.
Not a fit: People living outside the targeted local areas or those not at risk of overdose may not directly benefit from these local interventions.
Why it matters
Potential benefit: If successful, this could reduce overdose deaths and improve access to life-saving tools and local harm-reduction services in hard-hit communities.
How similar studies have performed: Previous efforts to expand naloxone distribution in Rhode Island, Massachusetts, and New York City have shown promise, though combining multiple harm-reduction tools and tailoring them across diverse locales is a newer approach.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZANG, XIAO — UNIVERSITY OF MINNESOTA
- Study coordinator: ZANG, XIAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.