NIH-funded research R01 grant

Synergizing Topological Deep Learning and Spatio-Temporal Causal Inference to Unpack Health

Official title: SCH: Synergizing Topological Deep Learning and Spatio-Temporal Causal Inference to Unpack Health

Funded at Harvard University D/b/a Harvard School of Public Health · NIH-11417181 · Data updated 2026-11-12

A team at a leading public health school is developing new data tools to better understand how environmental factors like air pollution and extreme weather affect health, using large, complex health data.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 6, 2024
Project endApril 30, 2028
Funding year2026
Award (this year)$281,043
NIH project number5R01ES037156-03
Project IDNIH-11417181 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to a specific patient population; this is a methodological grant for health data analysis.

Less likely to help

Direct patient participation is not described; benefits would come through improved public health insights.

What this research studies

Researchers will combine advanced deep learning with causal methods to analyze big, multi-resolution health data that include both individual and neighborhood information. The work aims to create practical tools and theory that can uncover how environmental exposures influence health outcomes across time and space. The project brings computer scientists and biostatisticians together to build a scalable framework for learning from spatiotemporal data and aggregated outcomes. The goal is to provide clearer insights into how environment shapes health, potentially informing policy and interventions.

Why it matters

Potential benefit: If successful, the tools could help public health officials and researchers pinpoint environmental risks and design targeted strategies to improve health outcomes.

How similar studies have gone: Previous work shows promise for combining topological methods with spatial statistics, but this project aims to advance the framework further.

Where this research is happening

  • Harvard University D/b/a Harvard School of Public Health
    Boston, United States
    Active

Researchers

  • Principal investigator: Dominici, Francesca — Harvard University D/b/a Harvard School of Public Health
  • Study coordinator: Dominici, Francesca

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.