Symptoms and quality of life during immunotherapy for metastatic cancer

Symptomatic Toxicities & Quality of Life among Individuals Receiving Immune Checkpoint Inhibitors for Metastatic Cancer.

NIH-funded research University of Miami School of Medicine · NIH-11267220

The team will track symptoms and day-to-day quality of life in people with metastatic cancer who are receiving immune checkpoint inhibitor treatments.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine NIH-funded
Lab location1 site (Coral Gables, United States)
Project IDNIH-11267220 on NIH RePORTER

What this research studies

If you join, you'll be asked to report symptoms and quality-of-life information while you receive immune checkpoint inhibitor therapy for metastatic cancer. The researchers will collect patient-reported outcome questionnaires over time and link those reports to clinical records about side effects, hospital visits, and treatment details. They will look for when symptoms start, which patients develop severe or late side effects, and how these problems affect daily life. The findings are meant to help doctors better manage immunotherapy side effects and support patients during and after treatment.

Who could benefit from this research

Good fit: Adults with metastatic solid tumors who are starting or currently receiving immune checkpoint inhibitor therapy would be the ideal candidates.

Not a fit: People who are not receiving immune checkpoint inhibitors, those with non-metastatic disease, or those unable to complete regular patient-reported questionnaires may not benefit directly from this project.

Why it matters

Potential benefit: If successful, this work could improve how clinicians spot and manage immunotherapy side effects, helping to protect quality of life for people on these treatments.

How similar studies have performed: Some previous studies have collected patient-reported symptoms during immunotherapy, but long-term, detailed linking of symptoms to clinical outcomes remains limited so this approach is still emerging.

Where this research is happening

Coral Gables, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CenterCancer TreatmentCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.