Surgery risk calculator for people with cirrhosis
Development and Validation of a Cirrhosis-specific Surgical Risk Calculator (C-SuRC)
Building a calculator that estimates the chance of death and complications after surgery for people who have cirrhosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Puget Sound Healthcare System NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11193256 on NIH RePORTER |
What this research studies
You would get a personalized estimate because researchers are building a cirrhosis-specific surgical risk calculator using a large national VA dataset that links pre-surgery health, liver function, and surgical details to outcomes. The team will combine cirrhosis-related, surgery-related, and other health factors into a prediction model and compare different modeling approaches. They will check the calculator's accuracy and calibration by comparing its predictions to past surgical outcomes. The goal is to help you and your surgical team choose safer options and address treatable problems before surgery.
Who could benefit from this research
Good fit: People with cirrhosis who are planning or considering elective or urgent surgery—especially Veterans receiving care in the VA system—are the ideal candidates for this work.
Not a fit: People without cirrhosis, patients whose care is outside the VA system, or those having rare procedures not well represented in the dataset may not get accurate predictions.
Why it matters
Potential benefit: If successful, this tool could help patients and surgeons make safer decisions, avoid high-risk operations, and address modifiable issues before surgery to lower complications and death.
How similar studies have performed: Existing general surgical risk calculators have helped surgical decision-making, but a cirrhosis-specific calculator is novel and has not been widely validated.
Where this research is happening
Seattle, United States
- VA Puget Sound Healthcare System — Seattle, United States (Active)
Researchers
- Principal investigator: Ioannou, George — VA Puget Sound Healthcare System
- Study coordinator: Ioannou, George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.