Supporting small ALS projects to speed treatments
Pilot-Feasibility
['FUNDING_OTHER'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11171890
This program funds small projects for people with ALS and related disorders to find and confirm clinical biomarkers and help get treatments ready for trials.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-11171890 on ClinicalTrials.gov |
What this research studies
This Pilot Core picks promising small clinical and translational projects aimed at speeding trial readiness for ALS and related disorders. It focuses especially on developing and validating biomarkers using patient samples and clinical data. Awarded teams join the CReATe Consortium, get help accessing consortium resources, and work with an independent review committee and patient advocacy partners. The core also helps projects secure necessary regulatory approvals and meet milestones so findings can move toward clinical trials.
Who could benefit from this research
Good fit: Ideal candidates are people with ALS or related motor neuron disorders (and sometimes at-risk family members for delayed-onset studies) who can provide clinical data or biospecimens and attend consortium visits.
Not a fit: People without ALS or related disorders, or those unable to provide samples or participate in study visits, are unlikely to receive direct benefit from the funded projects.
Why it matters
Potential benefit: If successful, this work could produce better biomarkers and speed the path to safer, more effective clinical trials for people with ALS.
How similar studies have performed: Previous CReATe and other biomarker-focused efforts have yielded promising ALS biomarkers, though translating biomarkers into approved therapies remains a work in progress.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BENATAR, MICHAEL — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: BENATAR, MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease, Disease Progression, Disorder