Support to reduce long-term emotional, thinking, and work problems after testicular cancer for young adults

A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

NIH-funded research University of California-Irvine · NIH-11338695

This project looks at how a therapy called Goal-focused Emotion-Regulation Therapy (GET) and stress-related biology relate to mental health, thinking, and work life in young adults who are long-term survivors of testicular cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11338695 on NIH RePORTER

What this research studies

You would join a study of 100 young adult testicular cancer survivors who were diagnosed between ages 18 and 39 and are at least five years past diagnosis. The team will collect questionnaires about mood, goal-setting, and work or career disruptions, and will measure stress-related biological markers and cognitive concerns. Researchers will link self-regulation skills (like emotion regulation and goal navigation) with biological stress signals and occupational outcomes to see what supports long-term resilience. The work builds on an existing therapy (GET) that helped recently treated survivors and aims to see whether those core processes matter years after treatment.

Who could benefit from this research

Good fit: Ideal candidates are people who were diagnosed with testicular cancer at ages 18–39 and are at least five years from their diagnosis.

Not a fit: People currently receiving active cancer treatment, those diagnosed as children or older than 39, or those less than five years from diagnosis are unlikely to be included or to directly benefit from this specific study.

Why it matters

Potential benefit: If successful, this work could point to targeted support or treatments to reduce long-term emotional distress, thinking problems, and work disruptions for young adult testicular cancer survivors.

How similar studies have performed: Earlier trials of GET in recently treated young adult testicular cancer survivors showed improved psychological outcomes and stress biology, but studying these links in survivors 5+ years out is new.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer ModelCancer SurvivorCancer SurvivorshipCancerModelCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.