NIH-funded research R01 grant

Support to reduce long-term emotional, thinking, and work problems after testicular cancer for young adults

Official title: A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

Funded at University of California-Irvine · NIH-11338695 · Data updated 2026-11-12

This project looks at how a therapy called Goal-focused Emotion-Regulation Therapy (GET) and stress-related biology relate to mental health, thinking, and work life in young adults who are long-term survivors of testicular cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine
NIH-funded
Lab location1 site (Irvine, United States)
Project startJuly 8, 2023
Project endJune 30, 2028
Funding year2025
Award (this year)$100,000
NIH project number3R01CA276143-03S1
Project IDNIH-11338695 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people who were diagnosed with testicular cancer at ages 18–39 and are at least five years from their diagnosis.

Less likely to help

People currently receiving active cancer treatment, those diagnosed as children or older than 39, or those less than five years from diagnosis are unlikely to be included or to directly benefit from this specific study.

What this research studies

You would join a study of 100 young adult testicular cancer survivors who were diagnosed between ages 18 and 39 and are at least five years past diagnosis. The team will collect questionnaires about mood, goal-setting, and work or career disruptions, and will measure stress-related biological markers and cognitive concerns. Researchers will link self-regulation skills (like emotion regulation and goal navigation) with biological stress signals and occupational outcomes to see what supports long-term resilience. The work builds on an existing therapy (GET) that helped recently treated survivors and aims to see whether those core processes matter years after treatment.

Why it matters

Potential benefit: If successful, this work could point to targeted support or treatments to reduce long-term emotional distress, thinking problems, and work disruptions for young adult testicular cancer survivors.

How similar studies have gone: Earlier trials of GET in recently treated young adult testicular cancer survivors showed improved psychological outcomes and stress biology, but studying these links in survivors 5+ years out is new.

Where this research is happening

  • University of California-Irvine
    Irvine, United States
    Active

Researchers

  • Principal investigator: Hoyt, Michael a — University of California-Irvine
  • Study coordinator: Hoyt, Michael a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.