Support hub for HIV and CMV vaccine development
Admin Core
This program supports work to develop and improve CMV-based vaccines to help prevent HIV infection in people at risk.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11127446 on NIH RePORTER |
What this research studies
From a patient perspective, this program aims to learn why a particular CMV-based vaccine stopped virus replication in animal tests and use those lessons to guide human vaccine development. The administrative core coordinates the different research projects, helps manage data and regulatory steps, and supports planning and communication between teams. Some parts of the program include early-phase human vaccine testing that volunteers can join, while other parts use lab and animal studies to refine the approach. Overall the work is meant to speed safe, organized progress toward vaccines that could protect people from HIV.
Who could benefit from this research
Good fit: Ideal candidates are adults willing to join early-phase vaccine trials, particularly those at risk for HIV infection and able to attend study visits.
Not a fit: People who are pregnant, severely immunocompromised, or not eligible for early-phase vaccine trials may not receive benefit or be allowed to participate.
Why it matters
Potential benefit: If successful, this work could lead to a new type of vaccine that prevents or controls HIV infection in people.
How similar studies have performed: Related CMV-based vaccine approaches produced strong protective signals in SIV (monkey) studies, but human CMV/HIV vaccine trials are still in early phases and unproven.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Picker, Louis J. — Oregon Health & Science University
- Study coordinator: Picker, Louis J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.