Support hub for fighting antibiotic-resistant infections

Administrative Core

['FUNDING_P01'] · MASSACHUSETTS EYE AND EAR INFIRMARY · NIH-11299015

Researchers are working together to find new ways to treat people with hospital-acquired infections that resist antibiotics.

Quick facts

Phase['FUNDING_P01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS EYE AND EAR INFIRMARY (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11299015 on ClinicalTrials.gov

What this research studies

This Harvard program focuses on infections caused by antibiotic-resistant staphylococci and enterococci, which are common causes of hospital-acquired infections. Scientists from math, systems biology, and clinical medicine use advanced lab methods, computational models, and clinical expertise to identify new treatment strategies. The Administrative Core keeps the effort running by coordinating teams, tracking progress and finances, and connecting the program to hospitals and other research initiatives. If you or a family member has a drug-resistant infection, this program could help create better treatment options down the line.

Who could benefit from this research

Good fit: Patients most relevant to this program are those hospitalized with multidrug-resistant staphylococcal or enterococcal infections (for example MRSA or VRE) or people at high risk for such infections.

Not a fit: People with non-resistant infections, community infections unrelated to hospital exposure, or conditions unrelated to staph/enterococcal disease are unlikely to receive direct benefit.

Why it matters

Potential benefit: If successful, this work could lead to new treatments or smarter use of existing antibiotics that reduce deaths and complications from drug-resistant hospital infections.

How similar studies have performed: Approaches like antibiotic stewardship, improved infection control, and some new or combination antibiotic therapies have helped in parts, but antibiotic resistance remains a major unresolved problem and systems-biology strategies are still emerging.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Communicable Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.