Super-high-resolution 10.5T brain MRI
Ultrahigh-resolution Functional MRI of the Human Brain at 10.5 Tesla
Creating ultra-detailed 10.5 Tesla MRI scans to let doctors and researchers see much smaller brain structures in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11251777 on NIH RePORTER |
What this research studies
If I participate, the team will build and test new radiofrequency coils and pulse sequences to get much sharper functional MRI images at 10.5T. They will combine advanced hardware (RF coils and gradients) with new pulse designs to reduce artifacts and speed up scans. The goal is to capture very small brain structures across whole or part of the brain at resolutions finer than standard clinical MRI. Volunteers will be scanned under strict safety checks while the methods are optimized for image quality and comfort.
Who could benefit from this research
Good fit: Adults who can safely undergo high-field MRI (no incompatible metal implants, pacemakers, or other MRI contraindications) and who can lie still for longer scans are ideal candidates, including healthy volunteers and people with neurological conditions who pass screening.
Not a fit: People with MRI-incompatible implants, severe claustrophobia, or inability to tolerate long scans are unlikely to be eligible or benefit from participation.
Why it matters
Potential benefit: If successful, this could allow earlier and more precise detection of subtle brain changes and improve how neurological and psychiatric conditions are understood and treated.
How similar studies have performed: Research using 7T MRI has already shown clearer detail than standard scanners, but pushing to 10.5T is novel and remains early-stage for human functional imaging.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Wu, Xiaoping — University of Minnesota
- Study coordinator: Wu, Xiaoping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.