NIH-funded research R01 grant

Substance use and health risks for pregnant and postpartum women

Official title: Substance use in PRegnancy and the mOrbidity Mortality rISk Environment (PROMISE)

Funded at Emory University · NIH-11325794 · Data updated 2026-11-12

This project maps when, where, and why pregnant and postpartum women who use drugs face health harms to guide better supports and services.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startJuly 1, 2024
Project endApril 30, 2029
Funding year2026
Award (this year)$702,932
NIH project number5R01DA059182-03
Project IDNIH-11325794 on NIH RePORTER

Who could benefit from this research

Could help

Women who are pregnant or within the first year after delivery and who use drugs (including opioids and amphetamines) are the primary focus for this work.

Less likely to help

People who are not pregnant or postpartum, those who do not use drugs, and men are unlikely to benefit directly from this project.

What this research studies

If you are pregnant or recently gave birth and use drugs, this research looks at who experiences harms, where those harms cluster, and when during pregnancy and the first year after birth they happen. The team will combine health records, death data, and other sources and use advanced mapping and statistical models to find hotspots and high-risk time windows. Researchers will also look at social and environmental factors that may increase risks so they can point to targets for future services. Findings are meant to help public health teams tailor supports to reach people at the right place and time.

Why it matters

Potential benefit: Could help target prevention and treatment services to reduce overdoses, complications, and maternal deaths among pregnant and postpartum women who use drugs.

How similar studies have gone: Researchers have used risk-environment approaches and spatial analyses in general drug-using populations, but applying these methods specifically to pregnant and postpartum women is novel.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Cooper, Hannah Lf — Emory University
  • Study coordinator: Cooper, Hannah Lf

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.