Studying how heat affects bats' immune responses to viruses
Official title: Developing a Chiropteran model to study the impact of thermal stress on antiviral immunity and inflammatory responses
Funded at Colorado State University · NIH-10949504 · Data updated 2026-11-12
This study is looking at how heat affects bats' immune systems when they get sick from viruses spread by mosquitoes, helping us learn more about how bats fight off these infections.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $125,238 |
| NIH project number | 1K01OD037645-01 |
| Project ID | NIH-10949504 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in the ecological and health implications of arboviral infections, particularly those with a focus on zoonotic diseases.
✕Less likely to help
Patients who are not affected by arboviral infections or have no interest in the ecological aspects of viral transmission may not benefit from this research.
What this research studies
This research focuses on developing a bat model to understand how thermal stress impacts the immune responses of bats to arboviral infections. The project aims to explore the interactions between bats, viruses, and the mosquitoes that transmit these viruses, using advanced technologies to monitor their responses with minimal disturbance. By examining how temperature affects these interactions, the research seeks to uncover important insights into viral immunity and inflammation in bats.
Why it matters
Potential benefit: If successful, this research could lead to better understanding of viral infections in bats, which may inform strategies for managing arboviral diseases in humans.
How similar studies have gone: While the specific approach of using bats as a model for thermal stress and viral immunity is novel, similar studies have shown success in understanding host-pathogen interactions in other animal models.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Fagre, Anna — Colorado State University
- Study coordinator: Fagre, Anna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.