Studying Alzheimer's disease in diverse populations in Los Angeles County
Official title: Leveraging the Electronic Health Record and Integrating Social and Biological Data to Expand Dementia Research in Understudied Populations in Los Angeles County
Funded at University of California Los Angeles · NIH-10913564 · Data updated 2026-11-12
This study is looking to learn more about Alzheimer's disease by including people from different backgrounds in Los Angeles, especially those who haven't been studied much before, so we can better understand how it affects everyone and make sure more voices are heard in dementia research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $550,883 |
| NIH project number | 5UH2AG083254-02 |
| Project ID | NIH-10913564 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from Hispanic/Latinx, Black, and Asian American/Pacific Islander backgrounds who are at risk for or diagnosed with Alzheimer's disease or related dementias.
✕Less likely to help
Patients who do not belong to the targeted understudied populations or those who do not have Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research aims to enhance our understanding of Alzheimer's disease and related dementias by focusing on diverse populations in Los Angeles County. The project utilizes electronic health records to identify and recruit individuals from traditionally understudied groups, including Hispanic/Latinx, Black, and Asian American/Pacific Islander communities. A multidisciplinary team will analyze social, environmental, genomic, and clinical factors to better understand the complexities of Alzheimer's disease. By collaborating with local primary care clinics and communities, the research seeks to lower barriers to participation and improve representation in dementia studies.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored interventions for Alzheimer's disease in diverse populations.
How similar studies have gone: Previous research has shown success in utilizing electronic health records to improve recruitment and understanding of diverse populations in health studies, making this approach promising.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Vossel, Keith Alan — University of California Los Angeles
- Study coordinator: Vossel, Keith Alan
Related research
Other NIH-funded projects on the same topics.
-
Investigating how DNA damage and repair mechanisms are altered in ALS and frontotemporal dementia.
This study is looking at how problems with DNA repair might contribute to conditions like ALS and frontotemporal dementia, and it’s testing ways to fix these issues in cells from patients to help develop new treatments.
-
Synthetic protein mimetics to treat Lewy Body Dementia
A new therapeutic approach using engineered protein-like molecules to block the harmful protein clumps that cause Lewy Body Dementia.
-
Dementia care staff study: adapting a US survey for use in many countries
A study is adapting and testing a survey for dementia care workers in the US, Brazil, Switzerland, and Ghana to help understand why workers stay in their jobs and how to improve care.
-
Dementia care staff study: adapting a survey for use in many countries
A multinational study will adapt and test a U.S. dementia-care worker survey in Brazil, Switzerland, and Ghana to help understand why staff stay in or leave long-term care settings.
-
Study of Dementia Care Staff in 4 Countries: Adapting Caregiver Surveys Across Cultures
A multinational project will adapt and test a dementia care worker survey so researchers can compare care environments across the US, Brazil, Switzerland, and Ghana.
-
New biomarkers to distinguish LATE from Alzheimer’s disease in dementia
A study to develop blood and CSF tests that can tell apart LATE from Alzheimer’s disease in people with dementia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.