Structured lifestyle programs to prevent type 2 diabetes in everyday settings
DP22-001 Real-world effectiveness of structured lifestyle interventions in preventing type 2 diabetes
This project compares different real-world lifestyle programs (like group, virtual, or online classes led by medical staff or trained coaches) to see which best help people with prediabetes avoid type 2 diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11113777 on NIH RePORTER |
What this research studies
You could join if you have prediabetes or a history of gestational diabetes. The team will examine Diabetes Prevention Program-style interventions delivered in routine settings, comparing group versus individual formats, who delivers the program (medical staff or trained lay leaders), and delivery mode (in-person, virtual, or online). Participants will be followed over time to track new diabetes cases, weight and activity changes, and program costs. The aim is to find which approaches work well and are affordable for people like you in real-world care and community settings.
Who could benefit from this research
Good fit: Ideal candidates are adults with prediabetes defined by fasting glucose 100–125 mg/dL, 2-hour glucose 140–199 mg/dL, hemoglobin A1c 5.7–6.7%, a high ADA/CDC risk score, or a history of gestational diabetes.
Not a fit: People without prediabetes or those with established type 2 diabetes are unlikely to be included or to benefit from the preventive programs studied.
Why it matters
Potential benefit: If successful, this work could show which lifestyle program formats most effectively prevent type 2 diabetes and are cost-effective in routine practice.
How similar studies have performed: The original Diabetes Prevention Program clinical trial showed a 58% reduction in diabetes incidence, and many community DPP programs have reported promising but variable short-term results while long-term, real-world effectiveness remains uncertain.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Herman, William H — University of Michigan at Ann Arbor
- Study coordinator: Herman, William H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.