Strengthening Hearts by Addressing Disrupted Sleep
Strengthening Hearts by Addressing DisruptEd Sleep (SHADES) Mechanistic Trial
This project explores how treating insomnia might help protect your heart and prevent heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11162411 on NIH RePORTER |
What this research studies
Heart disease is a major health concern, and current prevention methods aren't always enough. We believe that insomnia, a common sleep problem, might be a hidden risk factor for heart issues. This work looks at how insomnia could lead to heart problems through inflammation, nervous system imbalances, and metabolic changes. We are exploring if improving sleep with cognitive-behavioral therapy for insomnia (CBT-I) can reduce these risks and ultimately strengthen your heart.
Who could benefit from this research
Good fit: Ideal candidates might be adults aged 21 and older who experience insomnia and are at risk for cardiovascular disease.
Not a fit: Patients whose heart conditions are not related to sleep issues or who do not have insomnia may not directly benefit from this specific approach.
Why it matters
Potential benefit: If successful, this work could lead to new ways to prevent heart disease by focusing on better sleep.
How similar studies have performed: Previous work has shown that cognitive-behavioral therapy for insomnia can reduce markers of inflammation linked to heart disease.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Stewart, Jesse C — Indiana University Indianapolis
- Study coordinator: Stewart, Jesse C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.