Strategies to prevent opioid overdose deaths using data-driven modeling
Official title: Researching Effective Strategies to Prevent Opioid Death (RESPOND)
Funded at Boston Medical Center · NIH-11380863 · Data updated 2026-11-12
A patient-focused project tests how different policy and care delivery options could reduce overdose deaths by using advanced data to simulate real-world outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | June 1, 2018 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $797,674 |
| NIH project number | 5R01DA046527-09 |
| Project ID | NIH-11380863 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with opioid use disorder or individuals at risk of overdose, and communities considering MOUD and related interventions.
✕Less likely to help
If a community does not have MOUD access or if data inputs do not reflect local conditions, benefits may be limited.
What this research studies
This project uses a state-level simulation model to examine how policies and health care delivery changes affect opioid use disorder outcomes and costs. It leverages public health data and results from prior studies to forecast health and economic impacts of MOUD access and other interventions. The goal is to identify strategies that deliver the most benefit for people at risk of overdose while considering budget and equity across communities.
Why it matters
Potential benefit: If successful, the work could reveal cost-effective ways to save lives and reduce disparities for people with opioid use disorder.
How similar studies have gone: Prior work with RESPOND has projected benefits of expanding MOUD; this expansion seeks to adapt and extend those findings to more states.
Where this research is happening
-
Boston Medical Center
Boston, United States Active
Researchers
- Principal investigator: Linas, Benjamin P. — Boston Medical Center
- Study coordinator: Linas, Benjamin P.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.