Strategies to prevent opioid overdose deaths
Researching Effective Strategies to Prevent Opioid Death (RESPOND)
This project uses a computer simulation to compare ways of delivering opioid treatment to find which approaches could save lives for people with opioid use disorder.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11141645 on NIH RePORTER |
What this research studies
You should know that researchers are using a simulation model called RESPOND that combines public health data and findings from treatment studies to project what happens when policies or care delivery change. The team will update the model with state data and implementation-study results for places including Kentucky, Ohio, and New York to compare outcomes. The model looks at expanding access to medications for opioid use disorder in settings such as emergency departments and clinics, and it estimates effects on overdose deaths, costs, and health equity. Results are intended to guide health systems and policymakers toward strategies that reduce harm and use resources efficiently.
Who could benefit from this research
Good fit: People with opioid use disorder, especially those treated or seeking care in emergency departments, clinics, or community programs in Kentucky, Ohio, and New York, are the populations most relevant to this project.
Not a fit: People without opioid use disorder or those living in regions not covered by the model may not see direct benefit from this work.
Why it matters
Potential benefit: If successful, this work could point to policies and care models that reduce overdose deaths and improve access to effective medications for people with opioid use disorder.
How similar studies have performed: Previous RESPOND publications and other health-economic models have successfully projected public-health and cost impacts of expanding medications for opioid use disorder, though applying these tools to new states and specific implementation questions is relatively novel.
Where this research is happening
Boston, United States
- Boston Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Linas, Benjamin P. — Boston Medical Center
- Study coordinator: Linas, Benjamin P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.