Stopping drug-resistant germs in nursing homes

MDRO Carriage, Transmission, Sequelae, and Prevention in Nursing Homes

NIH-funded research University of California-Irvine · NIH-11332668

Testing ways to find and stop drug-resistant germs that affect nursing home residents and staff.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11332668 on NIH RePORTER

What this research studies

If I join, researchers may collect swabs from me and my environment and review medical records to see how drug-resistant germs spread. They will look at five important organisms (MRSA, VRE, ESBL-producing bacteria, CRE, and Candida auris) across many nursing homes and gather samples from residents, staff, and surfaces. Scientists will use laboratory testing, genomic sequencing, and computer models to track transmission and find key risk points. The team will combine those findings to design practical prevention steps for nursing homes and nearby hospitals.

Who could benefit from this research

Good fit: Ideal candidates are nursing home residents and staff at participating facilities, especially those with wounds, recent infections, frequent healthcare contacts, or known colonization.

Not a fit: People who do not live in or work at nursing homes or who have infections unrelated to the targeted drug-resistant organisms are unlikely to benefit directly.

Why it matters

Potential benefit: Could lead to better ways to prevent and control drug-resistant infections in nursing-home residents, lowering illness and spread.

How similar studies have performed: Smaller infection-control and genomic surveillance projects have reduced spread in some settings, but combining large-scale sampling, genomics, and modeling specifically in nursing homes is relatively new.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease ControlCenters for Disease Control and PreventionCenters for Disease Control and Prevention (U.S.)Communicable Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.