Stopping community drug-resistant infections
Combatting Community-Associated Antimicrobial Resistant Organisms Combat CA-ARO Study
This project looks for who in the community is getting drug-resistant bacterial infections and what raises their risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11281262 on NIH RePORTER |
What this research studies
The team will analyze medical records of people with urinary tract and bloodstream infections to find patterns tied to community-associated drug resistance. They will also enroll patients admitted to the hospital from the community and take clinical samples using special cultures to see how common resistant bacteria carriage is. Study staff will collect information about recent healthcare exposures, antibiotic use, and other possible risk factors to link findings to real-life behaviors and settings. Together these steps aim to point toward ways to reduce spread and prevent future infections.
Who could benefit from this research
Good fit: Ideal candidates are people admitted to participating hospitals from the community, especially those with urinary tract or bloodstream infections or recent antibiotic use or healthcare exposure.
Not a fit: People whose infections are clearly hospital-acquired or who do not receive care at participating hospitals are unlikely to directly benefit from participating.
Why it matters
Potential benefit: If successful, the work could help doctors and public health teams identify people at higher risk and design steps to lower community transmission of resistant bacteria.
How similar studies have performed: Previous studies have documented rising community rates of ESBL-producing bacteria, but targeted efforts linking clinical risk factors and active colonization screening in community patients are relatively new.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Kwon, Jennie H — Washington University
- Study coordinator: Kwon, Jennie H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.