Stopping cholera spread in African communities
Epidemiology and Ecology of Cholera in Africa
Researchers will track cholera bacteria and outbreaks to help communities in Africa stop transmission.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11508804 on NIH RePORTER |
What this research studies
This project collects samples from people, water, and the environment during cholera outbreaks in places such as Nigeria and Uganda. Lab testing reads the bacteria's genetic fingerprints and checks for viruses that affect cholera. Mapping tools show how specific cholera lineages move between districts and across borders. The team compares these spread patterns with local response actions to identify which measures help stop transmission.
Who could benefit from this research
Good fit: People living in cholera-affected districts in Nigeria or Uganda, especially those recently ill or living in outbreak hotspots, are the most likely candidates for participation.
Not a fit: People outside the targeted districts or countries, or those not included in the surveillance or sampling efforts, are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this work could help communities reduce and eventually eliminate cholera by pinpointing how the bacteria spread and which interventions stop outbreaks.
How similar studies have performed: Previous research has used genetic tracing and mapping to follow cholera spread, and the team's earlier R01 showed outbreaks often arrive from other areas, supporting this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sack, David a — Johns Hopkins University
- Study coordinator: Sack, David a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.