Spinal cord stimulation for nerve pain from chemotherapy and better cancer treatment
Spinal cord stimulation for the attenuation of chemotherapy-induced peripheral neuropathy and enhanced chemotherapeutic efficacy
This project explores how spinal cord stimulation might reduce nerve pain caused by chemotherapy and improve the effectiveness of cancer drugs.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11098559 on NIH RePORTER |
What this research studies
Many people undergoing chemotherapy experience debilitating nerve pain, known as chemotherapy-induced peripheral neuropathy (CIPN), which can feel like burning or tingling in the hands and feet. This project looks into whether spinal cord stimulation, a treatment often used for other types of nerve pain, could help prevent or lessen this pain. Researchers are also exploring if this stimulation could make chemotherapy more effective against cancer. The work will examine the body's immune and nervous system responses to understand how spinal cord stimulation might achieve these effects.
Who could benefit from this research
Good fit: Patients experiencing or at risk of chemotherapy-induced peripheral neuropathy, particularly those with non-small cell lung carcinoma, might be ideal candidates for future related studies.
Not a fit: Patients not undergoing chemotherapy or those without chemotherapy-induced nerve pain would likely not receive direct benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to manage severe nerve pain from chemotherapy and potentially enhance the power of cancer treatments.
How similar studies have performed: Spinal cord stimulation is an established treatment for other types of chronic nerve pain, but its specific utility for chemotherapy-induced pain and enhancing chemotherapy is still being explored.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sivanesan, Eellan — Johns Hopkins University
- Study coordinator: Sivanesan, Eellan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.