Speed-of-processing brain training to reduce memory problems in older adults
Cognitive training to reduce incidence of cognitive impairment in older adults
['FUNDING_R01'] · UNIVERSITY OF SOUTH FLORIDA · NIH-11224800
Computerized speed-of-processing brain training aims to help older adults lower their chances of developing mild cognitive impairment or dementia.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTH FLORIDA (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-11224800 on ClinicalTrials.gov |
What this research studies
You would be a cognitively normal older adult who may be randomly assigned to do computerized speed-of-processing training or to an active control of computer games. The program uses guided exercises on a computer to improve how quickly you process visual information. Clinicians will follow participants for several years and make clinical diagnoses of mild cognitive impairment or dementia as the main outcome. This large field effort builds on prior trials that showed cognitive and daily-living benefits and suggested lower long-term dementia risk.
Who could benefit from this research
Good fit: Ideal candidates are cognitively normal older adults (no diagnosis of MCI or dementia) who can use a computer and are willing to be followed for multiple years.
Not a fit: People who already have MCI or dementia, those unable to use a computer, or younger individuals are unlikely to benefit from this prevention-focused program.
Why it matters
Potential benefit: If successful, this could offer an accessible, non-drug approach that lowers older adults' risk of developing MCI or dementia.
How similar studies have performed: Prior randomized trials, including the ACTIVE trial, showed speed-of-processing training improved cognition and was linked to a reduced dementia risk over ten years, though earlier work lacked clinical diagnoses and used less rigorous controls.
Where this research is happening
TAMPA, UNITED STATES
- UNIVERSITY OF SOUTH FLORIDA — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: O'BRIEN, JENNIFER LEE — UNIVERSITY OF SOUTH FLORIDA
- Study coordinator: O'BRIEN, JENNIFER LEE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.