Software to improve the reliability of brain-related measurements in mental health research
PsyRAT: Extensible Open-Source Software for Applying Generalizability Theory to Assess Psychometric Reliability of Trial-Wise Scores and Optimize Tasks for RDoC
This study is creating free software to help make brain and muscle tests more reliable, so that doctors can give better diagnoses and treatment plans for mental health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10873191 on NIH RePORTER |
What this research studies
This research focuses on developing open-source software that applies generalizability theory to enhance the psychometric reliability of neural biomarkers used in mental health studies. By addressing measurement errors in biological assessments, the software aims to improve the validity of findings in clinical trials and genomic studies. Patients may benefit from more accurate diagnoses and treatment plans based on reliable biomarker data. The project will utilize advanced techniques such as EEG and EMG to optimize the tasks involved in measuring these biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals participating in clinical trials or studies involving neural biomarkers related to mental health disorders.
Not a fit: Patients who do not engage in clinical trials or do not have conditions assessed by the biomarkers being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more reliable and valid assessments of mental health conditions, improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown that applying generalizability theory can enhance the reliability of psychometric assessments, indicating a promising approach for this project.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Clayson, Peter Eugene — University of South Florida
- Study coordinator: Clayson, Peter Eugene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.