NIH-funded research R01 grant

Soft magnetoelastic microneedle patch for quick skin cancer screening

Official title: A soft magnetoelastic microneedle patch for rapid skin cancer screening

Funded at University of California Los Angeles · NIH-11299485 · Data updated 2026-11-12

This project will develop a soft, wearable microneedle patch that scans skin stiffness to help find skin cancer earlier in people with suspicious skin lesions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startApril 1, 2024
Project endMarch 31, 2029
Funding year2026
Award (this year)$351,039
NIH project number5R01CA287326-03
Project IDNIH-11299485 on NIH RePORTER

Who could benefit from this research

Could help

People with new, changing, or otherwise suspicious moles or skin lesions, or those with a history of skin cancer, would be the most likely candidates.

Less likely to help

Patients whose tumors lie deeper than about 5 mm under the skin or people without any skin lesions are unlikely to benefit from this device.

What this research studies

Researchers are building a soft, wearable patch with tiny microneedles that uses magnetic sensing to map how stiff the skin is across a lesion, because stiffness differences can signal cancer. The device is designed to rapidly scan a few square centimeters, reach depths up to about 5 mm, and give high-resolution stiffness maps. The team will optimize the patch design for scalability, test performance in mouse models of skin cancer, and then validate findings on excised human skin samples. If those steps are successful, the patch could be moved toward clinical use for screening, monitoring changes over time, or helping guide excisions.

Why it matters

Potential benefit: If successful, this could enable faster, non-invasive early detection and better monitoring or guidance for surgical removal of skin cancers.

How similar studies have gone: Tactile and stiffness-based approaches have shown promise in research, but this magnetic microneedle patch uses a new sensing mechanism and is largely novel and not yet tested in live patients.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Chen, Jun — University of California Los Angeles
  • Study coordinator: Chen, Jun

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.