Social support and dementia risk in sexual and gender minority adults

Social Convoys, Cognitive Reserve and Resilience, and Risk for Alzheimer's Disease and Related Dementias

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-11367854

Looks at how stress and social support relate to thinking skills and brain health in LGBTQ+ adults compared with straight, cisgender adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11367854 on NIH RePORTER

What this research studies

You would join a group of 300 sexual and gender minority adults (ages 25–85) who will answer questions about general stress, minority-related stress, social connections, and access to care. You would also complete standard cognitive tests and questionnaires about loneliness and support. Your results will be compared with 300 matched straight, cisgender participants from an ongoing aging study. Researchers will also run secondary analyses of existing MRI brain scans to explore possible differences in brain features between groups.

Who could benefit from this research

Good fit: Ideal candidates are sexual and gender minority adults aged 25–85 who can complete surveys and cognitive testing and are willing to share information about their social networks.

Not a fit: People with advanced dementia seeking immediate treatment, or those unwilling to complete interviews or cognitive tests, are unlikely to receive direct benefit from this observational project.

Why it matters

Potential benefit: Could identify social support features and service gaps that help protect cognitive health in LGBTQ+ people and guide future prevention efforts.

How similar studies have performed: Prior research shows social support helps cognitive aging in general, but targeted studies in sexual and gender minority groups are limited and the brain imaging comparisons are exploratory.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immunodeficiency Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.