Social life, health, and aging in older adults

National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4

NIH-funded research National Opinion Research Center · NIH-11318937

This project follows older Americans to learn how social life, activity, thinking skills, and health relate to risk and course of Alzheimer’s and other dementias.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNational Opinion Research Center NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11318937 on NIH RePORTER

What this research studies

You would be part of a long-term, national group of adults first enrolled in 2005–06 who provide information every few years about social relationships, mood, thinking, medical diagnoses, medicines, and daily activity. The project collects blood or other biological samples for research, uses wrist-worn accelerometers to measure sleep and movement, and conducts cognitive and health interviews. For people identified as higher risk of rapid decline, the team will do follow-up every two years rather than every five years, and they will include all Black and Hispanic participants regardless of age or health. Participation mostly involves interviews, brief tests, wearable activity monitoring, and occasional sample collection over time.

Who could benefit from this research

Good fit: Ideal participants are U.S. adults in the NSHAP cohort aged about 60–100, especially those flagged as higher risk for rapid health decline or dementia, and Black and Hispanic respondents who are included regardless of age.

Not a fit: People under the NSHAP age range, those living outside the U.S., or anyone seeking a treatment or cure are unlikely to get direct clinical benefit from participating in this observational project.

Why it matters

Potential benefit: If successful, this work could help identify early changes and social or activity patterns linked to faster cognitive decline so clinicians and families can offer support sooner.

How similar studies have performed: Long-running national cohorts like NSHAP and the Health and Retirement Study have produced important findings on aging and dementia, and this project builds on those proven methods by increasing follow-up for higher-risk participants.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's Disease and its related dementias
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.