NIH-funded research R01 grant

Social isolation and aging in people with schizophrenia

Official title: The impact of social isolation on aging health in schizophrenia

Funded at Icahn School of Medicine at Mount Sinai · NIH-11371709 · Data updated 2026-11-12

Looking at whether being socially isolated speeds up health problems as people with schizophrenia get older.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 15, 2022
Project endMay 31, 2027
Funding year2025
Award (this year)$73,375
NIH project number3R01MH128971-04S1
Project IDNIH-11371709 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 65 or older with a diagnosis of schizophrenia or a related psychotic disorder are the most appropriate candidates for this project.

Less likely to help

People without a psychotic disorder, much younger adults, or those unable to participate in follow-up visits are unlikely to receive direct benefit from this study.

What this research studies

If you join, you'll be followed over several years with regular check-ins about your social contacts, daily activities, and overall health. The team combines data from research centers in Europe and the US to create a longitudinal database of about 650 people, including roughly 500 with schizophrenia and 150 comparison participants. You'll be asked about loneliness and social connections, and researchers will review medical records and health measures to track aging-related conditions. The study aims to understand if isolation contributes to earlier health decline so future supports can be developed.

Why it matters

Potential benefit: If successful, this work could identify social connection as a modifiable factor to help delay or prevent health decline in older people with schizophrenia.

How similar studies have gone: Previous smaller studies and pilot data have linked social isolation to poorer health in schizophrenia, but long-term, multi-site evidence is still limited.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Reichenberg, Abraham — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Reichenberg, Abraham

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.