Social and emotional challenges for children who survived cancer early in life

Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects

NIH-funded research Research Inst Nationwide Children's Hosp · NIH-11294190

This project looks at how physical problems and thinking/learning difficulties after cancer treatment affect friendships, social life, and emotional wellbeing in people who had cancer as very young children.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp NIH-funded
Lab location1 site (Columbus, United States)
Project IDNIH-11294190 on NIH RePORTER

What this research studies

If you or your child survived cancer in early childhood, this work follows survivors to understand why they may have trouble making friends, feel isolated, or experience emotional distress. The team compares survivors who had brain tumors or CNS-directed treatments with those who did not, using cognitive tests, motor and sensory exams, and questionnaires about social experiences and mood. They also consider parent stress and how early treatment timing relates to later social skills. Findings will link specific physical and thinking problems to real-world social and emotional difficulties to guide future supports.

Who could benefit from this research

Good fit: Ideal participants are survivors who were diagnosed with cancer in early childhood (especially before age 6) and who received CNS-directed treatments or now have cognitive, motor, or social difficulties.

Not a fit: People who were not treated in early childhood or who did not have CNS-directed therapy, as well as those without social or cognitive late effects, are less likely to be included or directly helped by this project.

Why it matters

Potential benefit: If successful, the work could point to specific targets for therapies or school and family supports to help young survivors improve friendships and emotional health.

How similar studies have performed: Past research has identified social-cognitive problems in adult survivors and found limited success with interventions, so focusing on very early childhood survivors is a newer approach.

Where this research is happening

Columbus, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.