Soccer Heading and Brain Health

Heading and Soccer: Understanding Cognitive Risks, Benefits, and the Potential Mediating Role of White Matter

NIH-funded research Columbia University Health Sciences · NIH-11377861

This project looks at how heading the ball affects brain white matter and thinking in adult soccer players while also considering the benefits of aerobic fitness.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11377861 on NIH RePORTER

What this research studies

You'll be followed for two years as researchers track how often you head the ball, measure your aerobic fitness, and give brain MRI scans of white matter along with thinking tests. The team will enroll about 280 young adults and collect repeated imaging, cognitive, and exposure data over time. They will also look at personal factors, like genetics, that might change how heading and fitness affect the brain. The goal is to see whether white matter changes link heading exposure or fitness to changes in thinking.

Who could benefit from this research

Good fit: Adults (21+) who play soccer and are willing to travel to Columbia University for MRI scans, fitness testing, and cognitive assessments are ideal candidates.

Not a fit: People who do not play soccer or who cannot undergo MRI or clinic visits are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could help players, coaches, and clinicians weigh the brain risks of heading against the fitness benefits and guide safer play recommendations.

How similar studies have performed: Prior studies have found links between subconcussive heading and changes on brain scans and cognitive tests, but combining aerobic fitness measures and white matter mediation over time is relatively new.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.