Smoking-cessation support for people with HIV in South Africa

Evaluating smoking cessation interventions for PWH in South Africa: Efficacy, implementation, and cost-effectiveness.

['FUNDING_U01'] · JOHNS HOPKINS UNIVERSITY · NIH-11174261

This project offers evidence-based quitting programs to help adults living with HIV in South Africa stop smoking and finds the most practical and affordable ways to deliver them in HIV clinics.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11174261 on ClinicalTrials.gov

What this research studies

If you have HIV and smoke, this project adapts proven quitting programs to the local clinic setting so you can get tailored help. Participants will be offered counseling, medication or nicotine-replacement options and clinic-based supports while researchers measure stopping smoking with standard tests and follow-up visits. The team will also study how these services fit into routine HIV care and which approaches work best and cost the least. The aim is to make effective, affordable quitting help widely available in South African HIV clinics.

Who could benefit from this research

Good fit: Adults (typically 21 years or older) living with HIV who currently smoke and receive care at participating clinics in South Africa are the ideal candidates.

Not a fit: People who do not smoke, do not have HIV, are younger than the study's age cutoff, or cannot attend participating South African clinics are unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, the project could help many people with HIV quit smoking and reduce their risk of tuberculosis, heart disease, and lung disease.

How similar studies have performed: Evidence-based smoking-cessation programs have helped people quit in other low-resource settings, though adapting and scaling them specifically for people with HIV in South Africa is a newer effort.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.