NIH-funded research R01 grant

Smartphone quit-smoking program for American Indian and Alaska Native adults

Official title: Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trial

Funded at Fred Hutchinson Cancer Center · NIH-11170566 · Data updated 2026-11-12

This project tests a smartphone app based on Acceptance and Commitment Therapy to help American Indian and Alaska Native adults quit smoking compared with the NCI QuitGuide app.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 20, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$2,116,867
NIH project number4R01CA284687-03
Project IDNIH-11170566 on NIH RePORTER

Who could benefit from this research

Could help

American Indian or Alaska Native adults aged 21 or older who currently smoke and want help quitting are the ideal candidates.

Less likely to help

People who do not use smartphones, are younger than 21, or prefer non-digital cessation methods may not receive benefit from this app-based approach.

What this research studies

I would be randomly assigned to use either the iCanQuit app (an Acceptance and Commitment Therapy-based program) or the NCI QuitGuide app and follow the program on my own phone. The trial recruits American Indian and Alaska Native adults across the United States and collects regular follow-up information on smoking and abstinence. The team aims to reach people in remote areas with limited access to quitting services and provide a low-cost, widely available quitting tool. The work builds on earlier promising results for iCanQuit among AIAN participants.

Why it matters

Potential benefit: If successful, the app could help AIAN adults quit smoking by delivering accessible, culturally relevant support and reduce smoking-related illness.

How similar studies have gone: Preliminary data showed promising quit signals for the iCanQuit app among AIAN participants, but very few full-scale randomized trials have focused on this population.

Where this research is happening

  • Fred Hutchinson Cancer Center
    Seattle, United States
    Active

Researchers

  • Principal investigator: Bricker, Jonathan B — Fred Hutchinson Cancer Center
  • Study coordinator: Bricker, Jonathan B

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.