Smartphone quit-smoking program for American Indian and Alaska Native adults

Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trial

NIH-funded research Fred Hutchinson Cancer Center · NIH-11170566

This project tests a smartphone app based on Acceptance and Commitment Therapy to help American Indian and Alaska Native adults quit smoking compared with the NCI QuitGuide app.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11170566 on NIH RePORTER

What this research studies

I would be randomly assigned to use either the iCanQuit app (an Acceptance and Commitment Therapy-based program) or the NCI QuitGuide app and follow the program on my own phone. The trial recruits American Indian and Alaska Native adults across the United States and collects regular follow-up information on smoking and abstinence. The team aims to reach people in remote areas with limited access to quitting services and provide a low-cost, widely available quitting tool. The work builds on earlier promising results for iCanQuit among AIAN participants.

Who could benefit from this research

Good fit: American Indian or Alaska Native adults aged 21 or older who currently smoke and want help quitting are the ideal candidates.

Not a fit: People who do not use smartphones, are younger than 21, or prefer non-digital cessation methods may not receive benefit from this app-based approach.

Why it matters

Potential benefit: If successful, the app could help AIAN adults quit smoking by delivering accessible, culturally relevant support and reduce smoking-related illness.

How similar studies have performed: Preliminary data showed promising quit signals for the iCanQuit app among AIAN participants, but very few full-scale randomized trials have focused on this population.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.