NIH-funded research R01 grant

Smartphone game to help prevent HIV among teens with long-term follow-up booster

Official title: Efficacy Trial of a Smartphone Game to Prevent HIV among Young Africans: Long-Term Follow-Up with Developmentally Tailored Booster

Funded at Emory University · NIH-11541148 · Data updated 2026-11-12

A teen-friendly smartphone game called Tumaini is being studied to help prevent HIV in young people, now with plans to follow participants for several more years and add a booster tailored to their age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startSeptember 12, 2019
Project endJune 30, 2031
Funding year2026
Award (this year)$229,337
NIH project number3R01MH118982-06S1
Project IDNIH-11541148 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents and young adults who participated in or are similar to the Tumaini cohort and who are at risk for HIV exposure.

Less likely to help

Participants outside the target age range or those not at risk for HIV may derive little to no benefit.

What this research studies

This project builds on a large, multi-year trial in Kenya where nearly 1,000 adolescents played a theory-based game intended to reduce risky sexual behavior. The new plan follows the same cohort into late adolescence and early adulthood to see whether long-term effects persist and whether an age-appropriate booster enhances impact. Researchers will assess behavioral outcomes related to first sex and HIV prevention service access, while adapting content to participants’ changing developmental needs. The study aims to inform whether a scalable, low-cost digital intervention could support HIV prevention in other settings, including the US.

Why it matters

Potential benefit: If successful, the program could provide a cost-effective, scalable way to reduce HIV risk among adolescents and young adults.

How similar studies have gone: Past results showed positive effects on risk-reduction behaviors and intentions and high retention; long-term effects remain to be proven.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Winskell, S Kate — Emory University
  • Study coordinator: Winskell, S Kate

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.