Smartphone eye-photo checks to find malaria risk in schoolchildren

Risk stratification of malaria among school-age children with mHealth spectroscopy of blood analysis

NIH-funded research Purdue University · NIH-11142441

A low-cost smartphone photo of the inner eyelid plus a brief fever check will be used to flag school-age children in malaria-prone areas who most need a malaria rapid test.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-11142441 on NIH RePORTER

What this research studies

You or your child would have a quick photo taken of the inner eyelid with a basic smartphone and answer a few questions about recent fever or illness. An algorithm estimates blood hemoglobin from the photo and combines that with fever information to decide who should get a malaria rapid diagnostic test (RDT). The goal is to find children with malaria-linked anemia and catch infections that might be missed by routine screening while avoiding unnecessary RDTs. The project focuses on school-based screening in malaria-endemic parts of sub-Saharan Africa and will refine the phone-based hemoglobin method for this age group.

Who could benefit from this research

Good fit: Ideal candidates are school-age children (roughly primary and early secondary age, about 6–15 years) attending schools in malaria-endemic regions.

Not a fit: Infants, adults, people outside malaria-endemic areas, or anyone needing urgent medical care for severe illness are unlikely to benefit from this prescreening approach.

Why it matters

Potential benefit: If successful, this could enable cheaper, noninvasive prescreening that finds more hidden malaria infections in schoolchildren while reducing unnecessary tests.

How similar studies have performed: Rapid diagnostic tests are already effective for malaria and prior work has shown smartphone photos can estimate hemoglobin, but combining these tools as a prescreen for school programs is a newer approach.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.