Smart lower-leg clothing that tracks pressure inside prosthetic sockets

Towards Physical-Interface Pressure Monitoring Outside the Laboratory with Lower-Limb Electronic Clothing and Robust Optimization

NIH-funded research University of Notre Dame · NIH-11307148

This project develops smart lower-leg clothing and software to track pressure where a prosthetic socket meets the residual limb for people who use leg prostheses, including those with diabetes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Notre Dame NIH-funded
Lab location1 site (Notre Dame, United States)
Project IDNIH-11307148 on NIH RePORTER

What this research studies

If I wear this smart clothing it will use built-in fabric sensors, motion sensors, small load sensors, and computer models to figure out where and how hard my prosthetic socket presses on my residual limb. The system is being designed to run for more than 16 hours so it can record everyday activity outside the clinic and automatically calibrate itself so I don't need an expert to set it up. Researchers will combine sensor signals and biomechanical modeling to map pressure locations and magnitudes relative to my body. The goal is to give clinicians useful information that could help prevent sores or other problems from poorly fitting sockets.

Who could benefit from this research

Good fit: Ideal candidates are adults with lower-limb amputations who use prosthetic sockets regularly, especially people with reduced foot/limb sensation such as from diabetes or spinal cord injury, and who can wear sensors and complete out-of-clinic monitoring.

Not a fit: People without lower-limb amputations, those who use only upper-limb prostheses, or individuals unable to wear the clothing or attend required setup visits are unlikely to benefit from this work.

Why it matters

Potential benefit: If successful, this could help detect harmful pressure patterns during normal daily use and guide adjustments to reduce ulcers and other skin injuries.

How similar studies have performed: Previous work has used pressure sensors and smart textiles in lab settings with promising results, but long-term, user-worn continuous monitoring with automatic calibration outside the clinic is largely new.

Where this research is happening

Notre Dame, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.