Smart home system to monitor and personalize drug levels for epilepsy patients
Official title: SCH: Toward a smart, home-use system for noninvasive, personalized monitoring of drug levels
Funded at Oregon State University · NIH-11374906 · Data updated 2026-11-12
Alderly patients with epilepsy could have their anti-seizure drug levels monitored noninvasively at home using a smart system that gives real-time feedback to adjust dosing.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project start | September 1, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $278,791 |
| NIH project number | 5R01EB036841-03 |
| Project ID | NIH-11374906 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with epilepsy who are taking anti-seizure medications and whose care involves caregivers.
✕Less likely to help
Patients not using saliva-based monitoring or without access to the home-use system may not benefit.
What this research studies
This grant aims to create a home-use platform that measures drug levels noninvasively (via saliva) and provides real-time information to guide dosing. It combines AI and data science to build a personalized pharmacokinetic model and a user-friendly device/app that caregivers and patients can use. The team will develop electrochemical assays for saliva-based drug detection and integrate the measurements with clinical information to support safe, timely dose adjustments. Training of students and active engagement with caregivers are included to ensure the system meets patient needs and equity goals.
Why it matters
Potential benefit: If successful, patients could keep seizure control tighter with fewer blood draws and quicker dose adjustments.
How similar studies have gone: Prior work shows promise for noninvasive monitoring but this project adds real-time, home-based personalization and caregiver involvement.
Where this research is happening
-
Oregon State University
Corvallis, United States Active
Researchers
- Principal investigator: Ramsey, Stephen a. — Oregon State University
- Study coordinator: Ramsey, Stephen a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.