Smart control for powered above-knee prosthetic legs

Controlling Locomotion over Continuously Varying Activities for Agile Powered Prosthetic Legs

NIH-funded research University of Michigan at Ann Arbor · NIH-11229796

This project builds smarter control for powered above-knee prostheses to help people with leg amputations move more smoothly across different speeds, slopes, and steps.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11229796 on NIH RePORTER

What this research studies

From your point of view, researchers are creating computer models of how human joints move during everyday activities so a powered prosthetic knee can change behavior continuously instead of switching between a few fixed modes. They will collect movement and quick-perturbation data from able-bodied volunteers (and likely prosthesis users) and apply machine learning to identify how joint stiffness and damping should vary with walking phase and task. The new control rules will be implemented on powered prosthetic knees and tested so the device can adapt during steady walking, speed changes, and transitions like walking to stair climbing. The goal is a prosthesis that responds more naturally to you and your environment so walking feels smoother and safer.

Who could benefit from this research

Good fit: Ideal candidates would be adults with above-knee (transfemoral) amputations who use or are interested in trying powered prosthetic knees and can travel for device testing.

Not a fit: People without above-knee amputations, those who use only passive prostheses and cannot try powered devices, or those with medical issues preventing participation are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, this work could make powered above-knee prostheses feel more natural and stable across varied daily activities, reducing effort and improving mobility.

How similar studies have performed: Previous powered knee and ankle devices have shown promise for improving mobility, but continuously varying impedance based on phase/task modeling is a newer, less-tested approach.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.