NIH-funded research R01 grant

Smart contact lenses for monitoring eye pressure in glaucoma patients

Official title: Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care

Funded at Purdue University · NIH-11045646 · Data updated 2026-11-12

This study is testing new soft contact lenses that can keep track of eye pressure for people with glaucoma, helping them get better care by providing important information about their eye pressure, especially while they sleep.

More Glaucoma research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University
NIH-funded
Lab location1 site (West Lafayette, United States)
Project startMarch 1, 2024
Project endFebruary 29, 2028
Funding year2025
Award (this year)$511,258
NIH project number5R01EY034901-02
Project IDNIH-11045646 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with glaucoma or those at high risk of developing the condition.

Less likely to help

Patients with conditions unrelated to intraocular pressure or those who do not wear contact lenses may not benefit from this research.

What this research studies

This research focuses on developing innovative soft contact lenses that can continuously monitor intraocular pressure (IOP) in patients with glaucoma. By providing real-time data on IOP fluctuations, especially during sleep when pressure peaks may occur unnoticed, these lenses aim to enhance patient care and management of glaucoma. The study will involve optimizing the design and functionality of these smart lenses to ensure comfort and effectiveness for long-term wear. Patients will benefit from a more accurate understanding of their eye pressure patterns, which is crucial for preventing vision loss.

Why it matters

Potential benefit: If successful, this research could lead to improved management of glaucoma, potentially preventing vision loss and enhancing the quality of life for patients.

How similar studies have gone: Previous research on wearable ocular tonometers has shown promise, but this approach with smart contact lenses is relatively novel and untested.

Where this research is happening

  • Purdue University
    West Lafayette, United States
    Active

Researchers

  • Principal investigator: Lee, Chi Hwan — Purdue University
  • Study coordinator: Lee, Chi Hwan

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.