Sleep problems and heart health in World Trade Center Responders
Disturbed sleep and cardiovascular outcomes in World Trade Center Responders
This project looks at how sleep issues, especially sleep apnea, might affect the heart health of World Trade Center responders.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11074517 on NIH RePORTER |
What this research studies
Many World Trade Center responders experience poor sleep, and conditions like obstructive sleep apnea (OSA) can make this worse. Untreated OSA is linked to serious heart problems, similar to the general population. This work aims to understand if the risk of heart disease in responders with OSA is comparable to others. We also want to see if a specific blood marker, hs-CRP, can help predict future heart events in these individuals. Understanding these connections could lead to better ways to protect responders' heart health.
Who could benefit from this research
Good fit: This work focuses on World Trade Center General Responder Cohort members who experience poor sleep quality or have obstructive sleep apnea.
Not a fit: Patients who are not World Trade Center responders or do not have sleep-related issues would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could help identify World Trade Center responders at higher risk for heart disease due to sleep issues, allowing for earlier intervention and improved care.
How similar studies have performed: Previous work in the WTC-CHEST study has already shown a link between OSA risk and elevated hs-CRP levels in this population.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Sunderram, Jag — Rutgers Biomedical and Health Sciences
- Study coordinator: Sunderram, Jag
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.