Sleep patterns to monitor brain and heart health and risk of early death
Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and Mortality
This project uses AI on adults' sleep recordings to find new signals that could flag brain and heart problems and risk of earlier death.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11189688 on NIH RePORTER |
What this research studies
Researchers will collect and combine overnight sleep study data from hundreds of thousands of adults across several hospitals and link those records to health outcomes. They will train machine learning models to produce a Complete AI Sleep Report that standardizes scoring and extracts new, quantitative sleep biomarkers. The team will validate these biomarkers against clinical outcomes such as stroke, dementia, heart disease, and mortality and build a public data-sharing portal and tools for wider use.
Who could benefit from this research
Good fit: Adults aged 21 and older who have had or can undergo an overnight sleep study and are willing to share their sleep and medical records for research are the ideal candidates.
Not a fit: People under 21 or those without available sleep study or linked medical record data are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could help doctors spot brain and heart conditions earlier and give patients more precise sleep-based risk information.
How similar studies have performed: Smaller studies have linked sleep signals to brain and heart outcomes, but applying large-scale AI to hundreds of thousands of sleep records and public sharing at this scale is novel.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Westover, Michael Brandon — Beth Israel Deaconess Medical Center
- Study coordinator: Westover, Michael Brandon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.