Sleep, nighttime blood pressure, and dementia risk in Latino adults
Sleep in Neurocognitive Aging and Alzheimers Research (SANAR)
This work looks at whether sleep problems like obstructive sleep apnea and having blood pressure that doesn’t drop at night in Latino adults raise the chance of memory problems and Alzheimer's later on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11309108 on NIH RePORTER |
What this research studies
I would be part of a project focused on Latino adults that measures sleep breathing problems and overnight blood pressure patterns and follows thinking and memory over time. The team will use large community cohort data and new sleep and blood pressure measurements to track who develops cognitive decline. They pay special attention to midlife findings and differences by sex, since prior results suggested stronger links in younger women. The goal is to understand if treating sleep apnea or abnormal nighttime blood pressure in midlife could help lower dementia risk later.
Who could benefit from this research
Good fit: Latino adults aged 21 and older—especially middle-aged people and those with symptoms of sleep apnea or high blood pressure—are the ideal candidates for participation.
Not a fit: People who are not Latino, who have no sleep or blood-pressure concerns, or who want immediate clinical treatment rather than long-term risk information may not gain direct benefit from joining.
Why it matters
Potential benefit: If successful, this work could help identify treatable sleep and blood-pressure issues that lower Alzheimer's risk in Latino communities.
How similar studies have performed: Prior studies link obstructive sleep apnea and non-dipping blood pressure to stroke and cognitive decline, but few have followed Latino adults over time, so this builds on suggestive evidence rather than settled proof.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Ramos, Alberto Rafael — University of Miami School of Medicine
- Study coordinator: Ramos, Alberto Rafael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.