NIH-funded research R01 grant

Sleep and emotions in teens with PTSD

Official title: Sleep and emotion processing in adolescent Post-traumatic stress Disorder

Funded at University of Wisconsin-Madison · NIH-11248053 · Data updated 2026-11-12

This project looks at whether brain sleep patterns relate to how teens with PTSD process emotions and feel day-to-day.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison
NIH-funded
Lab location1 site (Madison, United States)
Project startMarch 15, 2024
Project endDecember 31, 2028
Funding year2026
Award (this year)$641,800
NIH project number5R01MH132221-03
Project IDNIH-11248053 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents aged 15–18 with a diagnosis of PTSD, though the study also enrolls trauma-exposed and typically developing teens for comparison.

Less likely to help

You may not benefit if you are outside the 15–18 age range, do not meet PTSD or comparison-group criteria, or have medical or sleep conditions that exclude participation.

What this research studies

You would join a study of 165 teens ages 15–18 divided into three groups: teens with PTSD, trauma-exposed peers, and typically developing peers. Researchers will record brain activity during sleep in the lab using a high-density 256-channel EEG before and after an emotional learning task, and you will also wear a portable EEG headband at home. The team will collect daily mood reports and measures of emotional responses to link daytime affect with nighttime brain signals. The approach is meant to reveal how sleep brain patterns support or interfere with emotional memory and daily mood after trauma.

Why it matters

Potential benefit: If successful, this work could point to sleep-based targets or timing for treatments to help emotional symptoms in teens with PTSD.

How similar studies have gone: Prior adult and some pediatric work links sleep and emotional memory, but this high-density EEG approach in adolescents with PTSD is relatively novel.

Where this research is happening

  • University of Wisconsin-Madison
    Madison, United States
    Active

Researchers

  • Principal investigator: Jones, Stephanie — University of Wisconsin-Madison
  • Study coordinator: Jones, Stephanie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.