Skin cancer risk and prediction for people with actinic keratoses
Official title: Skin Cancer Risks and Risk Prediction in Patients with Actinic Keratosis
Funded at University of Tx Md Anderson Can Ctr · NIH-11305992 · Data updated 2026-11-12
This project will build a prediction tool to estimate future skin cancer risk for people who have actinic keratoses.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | April 18, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $258,567 |
| NIH project number | 5K08CA263298-05 |
| Project ID | NIH-11305992 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with a diagnosis or history of actinic keratoses, especially those receiving care at participating clinics, are the main people this research focuses on.
✕Less likely to help
People without actinic keratoses or whose skin cancer risk stems from non–sun-related causes (for example, inherited syndromes) may not get direct benefit from this work.
What this research studies
Researchers will examine medical records and other patient data to determine how often people with actinic keratoses develop different types of skin cancer. They will document how doctors currently follow and screen patients with AKs to understand usual care patterns. Using those data, the team will create and test a risk prediction model that estimates an individual patient's chance of developing squamous cell carcinoma, basal cell carcinoma, or melanoma. The overall aim is to provide clear evidence to guide skin cancer surveillance and earlier detection for people with AKs.
Why it matters
Potential benefit: If successful, this work could help doctors target skin checks and early detection to the people with actinic keratoses who need them most.
How similar studies have gone: Prior studies link AKs to higher skin cancer risk, but a dedicated risk prediction model for patients with AKs has not been developed previously, making this a novel effort.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Wehner, Mackenzie Rachel — University of Tx Md Anderson Can Ctr
- Study coordinator: Wehner, Mackenzie Rachel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.