SISI sign-language program for children ages 5–8

Strategic and Interactive Signing Instruction (SISI): An intervention program to support sign language development in deaf children

NIH-funded research University of Tennessee Knoxville · NIH-11285276

This program teaches and supports sign language skills for deaf children ages 5–8 to help their communication, reading, memory, and school learning.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Knoxville NIH-funded
Lab location1 site (Knoxville, United States)
Project IDNIH-11285276 on NIH RePORTER

What this research studies

Your child would join a new program called SISI that uses strategic, interactive signing activities designed for young deaf children. The research team will develop and refine training and step-by-step instructions for teachers and caregivers who deliver the program. They will then pilot the program with children ages 5–8 to see how it affects signing, literacy, memory, and related skills. Activities may include guided signing practice, story-based interactions, and coaching for adults who support the child.

Who could benefit from this research

Good fit: Deaf children aged 5–8, especially those with limited sign language exposure or early language delays, are the intended participants.

Not a fit: Children older than 8, children who already have a solid foundation in sign language, or those unable to attend program sessions are less likely to benefit.

Why it matters

Potential benefit: If successful, SISI could help deaf children build stronger sign language and literacy skills and improve cognitive and academic outcomes.

How similar studies have performed: Similar strategic, interactive language programs have improved oral and written language skills in other groups, and early evidence links stronger sign language to better literacy, though targeted sign-focused trials are still emerging.

Where this research is happening

Knoxville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.