Simplifying mealtime diabetes management for adults with type 1 diabetes using new medications and technology.
Alleviating carbohydrate counting in adults with type 1 diabetes with weekly Semaglutide injections added to an automated insulin delivery with Lyumjev
This study is looking for ways to make life easier for adults with type 1 diabetes by testing a new method that combines weekly injections of Semaglutide with a smart insulin delivery system, so you can worry less about counting carbs at meals while still keeping your blood sugar in check.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mcgill University Health Ctr Res Inst NIH-funded |
| Lab location | 1 site (Montreal, Canada) |
| Project ID | NIH-10917039 on NIH RePORTER |
What this research studies
This research investigates how to make managing diabetes easier for adults with type 1 diabetes by combining weekly Semaglutide injections with an automated insulin delivery system using Lyumjev. The goal is to reduce the burden of carbohydrate counting at mealtimes, which can be challenging for many individuals. By using GLP-1 receptor agonists and a faster-acting insulin, the study aims to improve blood glucose control without increasing the risk of low blood sugar. Participants will be monitored to assess the effectiveness of this combined approach in managing their diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with type 1 diabetes.
Not a fit: Patients who do not have type 1 diabetes or those who are not able to participate in clinical trials may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly ease the daily management of diabetes for patients, leading to better blood sugar control and improved quality of life.
How similar studies have performed: Previous studies have shown that similar approaches using GLP-1 receptor agonists in type 2 diabetes have been successful, and recent data in type 1 diabetes also indicate promising results.
Where this research is happening
Montreal, Canada
- Mcgill University Health Ctr Res Inst — Montreal, Canada (Active)
Researchers
- Principal investigator: Tsoukas, Michael — Mcgill University Health Ctr Res Inst
- Study coordinator: Tsoukas, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.