Shorter, more informative brain MRI
Abbreviated yet enhanced neuro MRI protocol
['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11240353
This project aims to create an eight-minute brain MRI that gives detailed images for people who need head scans.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11240353 on ClinicalTrials.gov |
What this research studies
From a patient's point of view, the team is building a much faster brain scan that captures the usual pictures plus extra quantitative information in about eight minutes. The approach combines quicker imaging sequences and smart timing of the standard gadolinium contrast injection so the scan captures how the contrast moves through normal and abnormal tissue. The goal is to reduce typical 20–30 minute brain MRI slots by roughly three-fold while keeping or improving the image detail doctors use to make decisions. If successful, the plan could make MRI appointments quicker and more available without sacrificing diagnostic information.
Who could benefit from this research
Good fit: People scheduled for a clinical brain MRI—especially those who normally receive gadolinium contrast—would be the ideal candidates to try this protocol.
Not a fit: People who cannot undergo MRI (for example due to certain implanted devices or severe claustrophobia), who cannot receive gadolinium contrast (severe kidney problems), or who need very specialized brain imaging may not benefit from this protocol.
Why it matters
Potential benefit: If successful, this could make brain MRI much faster and more accessible while giving doctors the same or better information to guide care.
How similar studies have performed: Other teams have successfully sped up MRI using advanced image acquisition and reconstruction methods, but combining multiple quantitative contrasts and full contrast-enhancement into a single eight-minute clinical brain exam is a more novel step.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MADORE, BRUNO — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: MADORE, BRUNO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.