Shorter antibiotics for children's ear infections

RELAX: Reducing Length of Antibiotics For Children With Ear Infections

NIH-funded research Ihc Health Services, INC. · NIH-11195582

This compares two simple clinic approaches to help doctors prescribe shorter antibiotic courses for children with ear infections.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIhc Health Services, INC. NIH-funded
Lab location1 site (Murray, UNITED STATES)
Project IDNIH-11195582 on NIH RePORTER

What this research studies

This project tests two low-cost ways clinics can encourage 5–7 day antibiotic courses (instead of 10 days) for children aged 2 years and older with uncomplicated ear infections. One approach adds clinician education plus individualized audit-and-feedback with peer comparison and EHR prescription changes, while the other uses only EHR prescription changes. Researchers will track how often recommended short courses are prescribed, monitor return visits and side effects, and measure how easily each approach can be put into routine practice. The aim is to find an effective, low-resource method that reduces unnecessary antibiotic exposure.

Who could benefit from this research

Good fit: Children aged 2 years and older with non-severe acute otitis media seen at participating clinics are the ideal candidates.

Not a fit: Infants under 2 years, children with severe or complicated ear infections, or those who need longer antibiotic courses would likely not benefit from these shorter-duration strategies.

Why it matters

Potential benefit: If successful, the work could reduce unnecessary antibiotic days, lowering side effects and helping slow antibiotic resistance in children.

How similar studies have performed: Randomized trials and national guidelines already support 5–7 day courses for most children ≥2 years, and a prior pilot showed marked increases in short-duration prescribing using these intervention types.

Where this research is happening

Murray, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.