Short telehealth CBT to reduce loneliness for people with opioid use disorder

Addressing perceived social isolation as a novel therapeutic target among individuals with OUD using telehealth CBT

NIH-funded research University of Rochester · NIH-11320769

It sees if a brief, telehealth cognitive-behavioral program can reduce loneliness for people with opioid use disorder.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11320769 on NIH RePORTER

What this research studies

You would be invited to join a national program testing a short telehealth treatment aimed at reducing feelings of loneliness among people with opioid use disorder. Participants are randomly assigned to one of three options: therapist-led CBT for perceived social isolation, therapist-led health education, or self-guided health education, each delivered in six weekly sessions. Therapist-led sessions happen by video and the self-guided arm uses online materials. The team will track loneliness, mood, and opioid use over time to find which approach helps people feel more connected and supports recovery.

Who could benefit from this research

Good fit: Adults with opioid use disorder who report feeling socially isolated and can join weekly telehealth sessions are ideal candidates.

Not a fit: People who do not feel lonely, cannot use telehealth technology, or have unstable medical or psychiatric needs may not benefit from this specific program.

Why it matters

Potential benefit: If successful, this could help people with OUD feel less lonely and strengthen recovery by lowering relapse risk.

How similar studies have performed: CBT-based programs have reduced loneliness in other populations, but this is among the first fully powered trials testing such an approach specifically in people with OUD.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.