Shared database for people with osteosarcoma or leiomyosarcoma

Participant Engagement Unit

NIH-funded research Broad Institute, INC. · NIH-11196729

This project collects clinical records, tumor genomes, and patient-reported information from adults and children with osteosarcoma or leiomyosarcoma to speed new discoveries and trials.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBroad Institute, INC. NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-11196729 on NIH RePORTER

What this research studies

You can join an online project that partners with patients to gather medical records, tumor samples, and surveys about your experience. The team will sequence tumors and other genomic material, link that data to clinical outcomes, and store it in a shared database for researchers. Two patient-facing websites (one for osteosarcoma and one for leiomyosarcoma) will be used to consent participants and coordinate sample and data collection. The goal is to pool data from thousands of patients so researchers can find new targets and design better clinical trials.

Who could benefit from this research

Good fit: People of any age diagnosed with osteosarcoma or leiomyosarcoma who can provide consent (or have a caregiver provide consent for children) and share medical records or samples are ideal candidates.

Not a fit: People hoping for an immediate treatment or cure should know this is a data-collection and sharing effort rather than a therapeutic trial, so direct clinical benefit is unlikely right away.

Why it matters

Potential benefit: If successful, this could reveal new treatment targets, enable tailored clinical trials, and ultimately improve care for people with these rare sarcomas.

How similar studies have performed: Patient-partnered genomic registries in other cancers have led to useful discoveries and new trials, but assembling this scale of clinicogenomic data specifically for osteosarcoma and leiomyosarcoma is relatively new.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.